Recently , ldl apheresis has been applied in clinic and achieves a satisactory effect . in this dissertation , the tripeptide , serine - aspartic - glutamic acid ( sde ) , which existes in the cooh - terminal end of the seven repeats in the ligand binding domain of the ldl receptor and plays an important role in identifying ldl , was synthetized and immobilized onto the polyacrylamide ( paam ) beads as a bionic adsorbent for selective removal of ldl from plasma 本论文以丝氨酰-天冬氨酰-谷氨酸( sde )负电性三肽(此三肽广泛存在于ldl受体配体结合域7个重复序列的羧基末端，对ldl受体特异性识别ldl起着重要作用)作为配体固定到聚丙烯酰胺微球载体上制成仿生性ldl亲和吸附剂，考察其对人血浆中ldl及hdl的吸附功效。
Papaya each containing 100 grams of up to 529 mg of amino acids , aspartic acid 149 mg , 34 mg glutamic acid , arginine 31 mg , 28 mg valine , isoleucine 34 mg , 34 mg lysine , oleanolic acid 70 mg , 24 . 9 mg calcium , vc96 . 8 mg apple ' s 48 times , pectin 9 . 5 % , 16 . 8 % of total sugar , high nutrient content of papaya and other non - comparable papaya 每100克木瓜含氨基酸高达529毫克,其中门冬氨酸149毫克,谷氨酸34毫克,精氨酸31毫克,缬氨酸28毫克,异亮氨酸34毫克,赖氨酸34毫克,齐墩果酸70毫克,钙24 . 9毫克, vc96 . 8毫克是苹果的48倍,果胶9 . 5 % ,总糖16 . 8 % ,营养含量之高非番木瓜和其他木瓜可比。
Arginine feeding experiment showed that nitrogen metabolism in the s . tenebraius was obviously affected by arginine through two possible ways : ( l ) pronase activity in vitro could be influnced by arginine , as a result , the catabolism of nitrogen - containing macro - molecule was promoted and the nitrogen element in the broth was increased . ( 2 ) arginine could be transformed into glutamic acid , so that the biosynthesis of apramycin was promoted 因而我们认为gln可能是安普霉素生物合成氮元素的供体。 arg添加实验结果表明， arg可能通过两种途径影响黑暗链霉菌体内的氮代谢： ( 1 ) arg可能影响胞外蛋白酶的活性，进而促进含氮大分子物质的分解代谢，补充发酵过程中的氮素来源。
The feeding of glutamic acid , glutamine and a - keto - glutaric acid respectively showed that glutamic acid and glutamine had no obvious effects on cell growth , but stimulated apramycin production greatly . with the same concentration of amino acids supplemented , glutamine showed a stronger stimulation effect than glutamic acid , while a - keto - glutaric acid showed a repression effect on apramycin production . it could be deduced from above results that glutamine possibly is the donor of nitrogen element for the biosynthesis of apramycin Glu 、 gln及?酮戊二酸添加实验结果表明glu 、 gln对菌体的生长无明显的影响，但能强烈促进安普霉素的生物合成，且相同浓度条件下gln的促进作用明显高于glu ，而?酮戊二酸则对安普霉素的生物合成有抑制作用。
